MetaCyc Pathway: 5-(methoxycarbonylmethoxy)uridine biosynthesis in Erwinia tracheiphila SCR3

prephenate + S-adenosyl-L-methionine→S-adenosyl-S-carboxymethyl-L-homocysteine + 3-phenyl-2-oxopropanoate + H₂O

S-adenosyl-S-carboxymethyl-L-homocysteine + a 5-hydroxyuridine³⁴ in tRNA→a 5-(carboxymethoxy)uridine³⁴ in tRNA + S-adenosyl-L-homocysteine + H⁺

LU632_RS13460 (cmoB)

a 5-(carboxymethoxy)uridine³⁴ in tRNA + S-adenosyl-L-methionine→a 5-(methoxycarbonylmethoxy)uridine³⁴ in tRNA + S-adenosyl-L-homocysteine (EC 2.1.1.M28)

LU632_RS09865 (cmoM)

Links:

Pathway details at MetaCyc
Fitness data for 3 genes
Select organism:
All MetaCyc pathways for Erwinia tracheiphila SCR3

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information