| a mature peptidoglycan (meso-DAP containing)→a mature peptidoglycan (meso-DAP containing) + GlcNAc-1,6-anhMurNAc-L-Ala-γ-D-Glu-meso-DAP-D-Ala (EC 4.2.2.f) |
| LU632_RS01075 (mltD) |
| LU632_RS02575 (sltY) |
| LU632_RS05410 (mltC) |
| LU632_RS06225 (mltA) |
| LU632_RS14005 |
| LU632_RS15745 (mltB) |
| LU632_RS17980 (mltF) |
| GlcNAc-1,6-anhMurNAc-L-Ala-γ-D-Glu-meso-DAP-D-Ala[out] + H+[out]→GlcNAc-1,6-anhMurNAc-L-Ala-γ-D-Glu-meso-DAP-D-Ala[in] + H+[in] |
| LU632_RS18370 (ampG) |
N-acetylmuramoyl-L-alanine amidase:
GlcNAc-1,6-anhMurNAc-L-Ala-γ-D-Glu-meso-DAP-D-Ala + H2O→N-acetyl-β-D-glucosamine-1,6-anhydro-N-acetyl-β-D-muramate + L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanine (EC 3.5.1.28) |
| LU632_RS00215 |
| LU632_RS02040 (amiB) |
| LU632_RS06215 (amiC) |
| LU632_RS11910 |
| LU632_RS15790 |
Beta-N-acetylhexosaminidase:
N-acetyl-β-D-glucosamine-1,6-anhydro-N-acetyl-β-D-muramate + H2O→1,6-anhydro-N-acetyl-β-D-muramate + N-acetyl-D-glucosamine (EC 3.2.1.52) |
| LU632_RS14755 (nagZ) |
| LU632_RS16220 |
Muramoyltetrapeptide carboxypeptidase:
L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanine + H2O→L-alanyl-γ-D-glutamyl-meso-diaminopimelate + D-alanine (EC 3.4.17.13) |
| LU632_RS14010 (ldcA) |
| 1,6-anhydro-N-acetyl-β-D-muramate + ATP + H2O→N-acetyl-D-muramate 6-phosphate + ADP + H+ (EC 2.7.1.170) |
| LU632_RS11250 (anmK) |
| N-acetyl-D-muramate 6-phosphate + H2O→N-acetyl-D-glucosamine 6-phosphate + (R)-lactate (EC 4.2.1.126) |
| LU632_RS17995 (murQ) |
N-acetylglucosamine-6-phosphate deacetylase:
N-acetyl-D-glucosamine 6-phosphate + H2O→D-glucosamine 6-phosphate + acetate (EC 3.5.1.25) |
| LU632_RS16250 (nagA) |
Phosphoglucosamine mutase:
D-glucosamine 6-phosphate→α-D-glucosamine 1-phosphate (EC 5.4.2.10) |
| LU632_RS21090 (glmM) |
Glucosamine-1-phosphate N-acetyltransferase:
α-D-glucosamine 1-phosphate + acetyl-CoA→N-acetyl-α-D-glucosamine 1-phosphate + coenzyme A + H+ (EC 2.3.1.157) |
| LU632_RS24870 (glmU) |
UDP-N-acetylglucosamine diphosphorylase:
N-acetyl-α-D-glucosamine 1-phosphate + H+ + UTP→UDP-N-acetyl-α-D-glucosamine + diphosphate (EC 2.7.7.23) |
| LU632_RS24870 (glmU) |
UDP-N-acetylglucosamine 1-carboxyvinyltransferase:
UDP-N-acetyl-α-D-glucosamine + phosphoenolpyruvate→UDP-N-acetyl-α-D-glucosamine-enolpyruvate + phosphate (EC 2.5.1.7) |
| LU632_RS21215 (murA) |
| UDP-N-acetyl-α-D-glucosamine-enolpyruvate + NADPH + H+→UDP-N-acetyl-α-D-muramate + NADP+ (EC 1.3.1.98) |
| LU632_RS19515 (murB) |
| L-alanyl-γ-D-glutamyl-meso-diaminopimelate + UDP-N-acetyl-α-D-muramate + ATP→UDP-MurNAc-L-Ala-γ-D-Glu-meso-DAP + ADP + H+ + phosphate (EC 6.3.2.45) |
| LU632_RS02135 (mpl) |
Links:
Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information