MetaCyc Pathway: superpathway of D-glucarate and D-galactarate degradation in Erwinia tracheiphila SCR3

Add experiment(s):


Galactarate dehydratase:
galactarate→5-dehydro-4-deoxy-D-glucarate + H2O (EC 4.2.1.42)
LU632_RS06305 (garD)
Glucarate dehydratase:
D-glucarate→5-dehydro-4-deoxy-D-glucarate + H2O (EC 4.2.1.40)
LU632_RS06315
LU632_RS06320 (gudD)
2-dehydro-3-deoxyglucarate aldolase:
5-dehydro-4-deoxy-D-glucarate→(2R)-tartronate semialdehyde + pyruvate (EC 4.1.2.20)
LU632_RS06325 (garL)
2-hydroxy-3-oxopropionate reductase (in reverse):
(2R)-tartronate semialdehyde + NAD(P)H + H+→D-glycerate + NAD(P)+ (EC 1.1.1.60)
LU632_RS06330 (garR)
D-glycerate + ATP→2-phospho-D-glycerate + ADP + H+ (EC 2.7.1.165)
LU632_RS06335

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information