MetaCyc Pathway: L-valine biosynthesis in Enterobacter asburiae PDN3

Add experiment(s):


Acetolactate synthase:
2 pyruvate + H+→(S)-2-acetolactate + CO2 (EC 2.2.1.6)
EX28DRAFT_2402
EX28DRAFT_3673
EX28DRAFT_3674
EX28DRAFT_3953
EX28DRAFT_3954
EX28DRAFT_4440
EX28DRAFT_4441
Ketol-acid reductoisomerase (in reverse):
(S)-2-acetolactate + NADPH + H+→(2R)-2,3-dihydroxy-3-methylbutanoate + NADP+ (EC 1.1.1.86)
EX28DRAFT_4446
Dihydroxy-acid dehydratase:
(2R)-2,3-dihydroxy-3-methylbutanoate→3-methyl-2-oxobutanoate + H2O (EC 4.2.1.9)
EX28DRAFT_3455
EX28DRAFT_4443
Branched-chain-amino-acid transaminase (in reverse):
3-methyl-2-oxobutanoate + L-glutamate→L-valine + 2-oxoglutarate (EC 2.6.1.42)
EX28DRAFT_4442

Links:

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information