MetaCyc Pathway: superpathway of L-arginine and L-ornithine degradation in Enterobacter asburiae PDN3

Arginine decarboxylase: L-arginine + H+→agmatine + CO2 (EC 4.1.1.19)

EX28DRAFT_2978

Ornithine decarboxylase: L-ornithine + H+→putrescine + CO2 (EC 4.1.1.17)

EX28DRAFT_2285

EX28DRAFT_3012

Agmatinase: agmatine + H2O→putrescine + urea (EC 3.5.3.11)

EX28DRAFT_2977

Putrescine aminotransferase: putrescine + 2-oxoglutarate→4-aminobutanal + L-glutamate (EC 2.6.1.82)

EX28DRAFT_3140

Glutamate--putrescine ligase: putrescine + ATP + L-glutamate→γ-glutamyl-L-putrescine + ADP + H+ + phosphate (EC 6.3.1.11)

EX28DRAFT_1498

Aminobutyraldehyde dehydrogenase: 4-aminobutanal + NAD+ + H2O→4-aminobutanoate + NADH + 2 H+ (EC 1.2.1.19)

EX28DRAFT_1030

EX28DRAFT_1501

EX28DRAFT_3516

4-aminobutanal→1-pyrroline + H2O (spontaneous)

No genes

γ-glutamyl-L-putrescine + dioxygen + H2O→4-(γ-L-glutamylamino)butanal + ammonium + hydrogen peroxide (EC 1.4.3.M3)

EX28DRAFT_1502

4-(γ-L-glutamylamino)butanal + NAD(P)+ + H2O→4-(γ-L-glutamylamino)butanoate + NAD(P)H + 2 H+ (EC 1.2.1.99)

EX28DRAFT_1501

Gamma-glutamyl-gamma-aminobutyrate hydrolase: 4-(γ-L-glutamylamino)butanoate + H2O→4-aminobutanoate + L-glutamate (EC 3.5.1.94)

EX28DRAFT_1499

4-aminobutyrate transaminase: 4-aminobutanoate + 2-oxoglutarate→succinate semialdehyde + L-glutamate (EC 2.6.1.19)

EX28DRAFT_1503

EX28DRAFT_4294

Succinate-semialdehyde dehydrogenase: succinate semialdehyde + NAD+ + H2O→succinate + NADH + 2 H+ (EC 1.2.1.24)

EX28DRAFT_1198

EX28DRAFT_1501

EX28DRAFT_3530

succinate semialdehyde + NADP+ + H2O→succinate + NADPH + 2 H+ (EC 1.2.1.79)

No genes

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information