MetaCyc Pathway: O-antigen building blocks biosynthesis (E. coli) in Enterobacter asburiae PDN3

Add experiment(s):


UDP-galactopyranose mutase:
UDP-α-D-galactose→UDP-α-D-galactofuranose
(EC 5.4.99.9)
No genes
Glucose-6-phosphate isomerase:
α-D-glucose 6-phosphate→β-D-fructofuranose 6-phosphate
(EC 5.3.1.9)
EX28DRAFT_2922
EX28DRAFT_4318
Phosphoglucomutase (in reverse):
D-glucopyranose 6-phosphate→α-D-glucopyranose 1-phosphate
(EC 5.4.2.2)
EX28DRAFT_2287
EX28DRAFT_3227
Glucose-1-phosphate thymidylyltransferase:
α-D-glucopyranose 1-phosphate + H+ + dTTP→dTDP-α-D-glucose + diphosphate
(EC 2.7.7.24)
EX28DRAFT_0527
Glutamine--fructose-6-phosphate transaminase (isomerizing):
β-D-fructofuranose 6-phosphate + L-glutamine→D-glucosamine 6-phosphate + L-glutamate
(EC 2.6.1.16)
EX28DRAFT_4005
Phosphoglucosamine mutase:
D-glucosamine 6-phosphate→α-D-glucosamine 1-phosphate
(EC 5.4.2.10)
EX28DRAFT_3227
dTDP-glucose 4,6-dehydratase:
dTDP-α-D-glucose→dTDP-4-dehydro-6-deoxy-α-D-glucopyranose + H2O
(EC 4.2.1.46)
EX28DRAFT_0515
EX28DRAFT_0521
EX28DRAFT_0531
Glucosamine-1-phosphate N-acetyltransferase:
α-D-glucosamine 1-phosphate + acetyl-CoAN-acetyl-α-D-glucosamine 1-phosphate + coenzyme A + H+
(EC 2.3.1.157)
EX28DRAFT_4006
dTDP-4-dehydrorhamnose 3,5-epimerase:
dTDP-4-dehydro-6-deoxy-α-D-glucopyranose→dTDP-4-dehydro-β-L-rhamnose
(EC 5.1.3.13)
EX28DRAFT_0520
dTDP-4-dehydrorhamnose reductase (in reverse):
dTDP-4-dehydro-β-L-rhamnose + NADPH + H+→dTDP-β-L-rhamnose + NADP+
(EC 1.1.1.133)
No genes
UDP-N-acetylglucosamine diphosphorylase:
N-acetyl-α-D-glucosamine 1-phosphate + H+ + UTP→UDP-N-acetyl-α-D-glucosamine + diphosphate
(EC 2.7.7.23)
EX28DRAFT_4006

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information