MetaCyc Pathway: coenzyme A biosynthesis I (bacteria) in Enterobacter asburiae PDN3

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Phosphopantothenate--cysteine ligase:
(R)-4'-phosphopantothenate + CTP + L-cysteine→(R)-4'-phosphopantothenoyl-L-cysteine + CMP + diphosphate + H+
(EC 6.3.2.5)
EX28DRAFT_3889
Phosphopantothenoylcysteine decarboxylase:
(R)-4'-phosphopantothenoyl-L-cysteine + H+→4'-phosphopantetheine + CO2
(EC 4.1.1.36)
EX28DRAFT_3889
Pantetheine-phosphate adenylyltransferase:
4'-phosphopantetheine + ATP + H+→3'-dephospho-CoA + diphosphate
(EC 2.7.7.3)
EX28DRAFT_3884
Dephospho-CoA kinase:
3'-dephospho-CoA + ATP→coenzyme A + ADP + H+
(EC 2.7.1.24)
EX28DRAFT_3697

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information