MetaCyc Pathway: D-fructuronate degradation in Escherichia coli HS(pFamp)R (ATCC 700891)

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Fructuronate reductase (in reverse):
D-fructuronate + NADH + H+→D-mannonate + NAD+ (EC 1.1.1.57)
OHPLBJKB_01537
OHPLBJKB_02170
OHPLBJKB_03744
Mannonate dehydratase:
D-mannonate→2-dehydro-3-deoxy-D-gluconate + H2O (EC 4.2.1.8)
OHPLBJKB_03745
2-dehydro-3-deoxy-D-gluconate + ATP→2-dehydro-3-deoxy-D-gluconate 6-phosphate + ADP + H+ (EC 2.7.1.178; 2.7.1.45)
OHPLBJKB_00176
2-dehydro-3-deoxy-phosphogluconate aldolase:
2-dehydro-3-deoxy-D-gluconate 6-phosphate→D-glyceraldehyde 3-phosphate + pyruvate (EC 4.1.2.14; 4.1.2.55)
OHPLBJKB_01879

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information