MetaCyc Pathway: pyruvate fermentation to ethanol III in Escherichia coli HS(pFamp)R (ATCC 700891)

Pyruvate synthase:
pyruvate + coenzyme A + 2 an oxidized ferredoxin [iron-sulfur] cluster→acetyl-CoA + CO₂ + H⁺ + 2 a reduced ferredoxin [iron-sulfur] cluster (EC 1.2.7.1)

OHPLBJKB_02334

Acetaldehyde dehydrogenase (acetylating) (in reverse):
acetyl-CoA + NADH + H⁺→acetaldehyde + coenzyme A + NAD⁺ (EC 1.2.1.10)

OHPLBJKB_01276

OHPLBJKB_02444

OHPLBJKB_03320

Alcohol dehydrogenase (in reverse):
acetaldehyde + NADH + H⁺→ethanol + NAD⁺ (EC 1.1.1.1)

Links:

Pathway details at MetaCyc
Fitness data for 11 genes
Select organism:
All MetaCyc pathways for Escherichia coli HS(pFamp)R (ATCC 700891)

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information