MetaCyc Pathway: L-citrulline degradation in Escherichia coli HS(pFamp)R (ATCC 700891)

Ornithine carbamoyltransferase (in reverse):
L-citrulline + H⁺ + phosphate→carbamoyl phosphate + L-ornithine (EC 2.1.3.3)

OHPLBJKB_03782

Carbamate kinase (in reverse):
carbamoyl phosphate + ADP→carbamate + ATP (EC 2.7.2.2; 6.3.4.16; 6.3.5.5)

OHPLBJKB_00841

carbamate + 2 H⁺→CO₂ + ammonium (spontaneous) (EC 3.5.1.110; 3.5.1.20; 3.5.1.54; 4.2.1.104)

OHPLBJKB_03005

OHPLBJKB_03006

OHPLBJKB_03331

Links:

Pathway details at MetaCyc
Fitness data for 9 genes
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All MetaCyc pathways for Escherichia coli HS(pFamp)R (ATCC 700891)

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information