MetaCyc Pathway: superpathway of N-acetylglucosamine, N-acetylmannosamine and N-acetylneuraminate degradation in Escherichia coli ECRC99

Add experiment(s):


N-acetyl-β-neuraminate→aceneuramate (EC 5.1.3.24)
KEDOAH_10280 (nanQ)
N-acetylneuraminate lyase:
aceneuramate→N-acetyl-D-mannosamine + pyruvate (EC 4.1.3.3)
KEDOAH_10300 (nanA)
N-acylmannosamine kinase:
N-acetyl-D-mannosamine + ATP→N-acetyl-D-mannosamine 6-phosphate + ADP + H+ (EC 2.7.1.60)
KEDOAH_10285 (nanK)
N-acylglucosamine-6-phosphate 2-epimerase:
N-acetyl-D-mannosamine 6-phosphate→N-acetyl-D-glucosamine 6-phosphate (EC 5.1.3.9)
KEDOAH_10290 (nanE)
N-acetylglucosamine-6-phosphate deacetylase:
N-acetyl-D-glucosamine 6-phosphate + H2O→D-glucosamine 6-phosphate + acetate (EC 3.5.1.25)
KEDOAH_09840 (nagA)
KEDOAH_20805 (nagA)
Glucosamine-6-phosphate deaminase:
D-glucosamine 6-phosphate + H2O→β-D-fructofuranose 6-phosphate + ammonium (EC 3.5.99.6)
KEDOAH_20810 (nagB)

Links:

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information