MetaCyc Pathway: L-tyrosine biosynthesis I in Escherichia coli ECRC98

Add experiment(s):


Chorismate mutase:
chorismate→prephenate (EC 5.4.99.5)
JDDGAC_24885 (tyrA)
JDDGAC_24890 (pheA)
Prephenate dehydrogenase:
prephenate + NAD+→3-(4-hydroxyphenyl)pyruvate + CO2 + NADH (EC 1.3.1.12)
JDDGAC_24885 (tyrA)
Aspartate transaminase (in reverse):
3-(4-hydroxyphenyl)pyruvate + L-glutamate→L-tyrosine + 2-oxoglutarate (EC 2.6.1.1; 2.6.1.27; 2.6.1.5; 2.6.1.57)
JDDGAC_04070 (ydcR)
JDDGAC_08995 (aspC)
JDDGAC_15045 (yjiR)
JDDGAC_16555 (tyrB)
JDDGAC_24515 (aRO8)
JDDGAC_28620 (hisC)

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information