MetaCyc Pathway: adenosine nucleotides degradation II in Escherichia coli ECRC98

Add experiment(s):


5'-nucleotidase:
AMP + H2O→adenosine + phosphate (EC 3.1.3.5)
JDDGAC_11755 (ushA)
JDDGAC_12280 (phoA)
JDDGAC_14880 (yjjG)
JDDGAC_16545 (aphA)
JDDGAC_24145 (surE)
JDDGAC_26785 (yfbR)
Adenosine deaminase:
adenosine + H+ + H2O→inosine + ammonium (EC 3.5.4.4)
JDDGAC_02170 (add)
JDDGAC_24920 (yfiH)
Purine-nucleoside phosphorylase:
inosine + phosphate→hypoxanthine + α-D-ribose-1-phosphate (EC 2.4.2.1)
JDDGAC_12240 (ppnP)
JDDGAC_14810 (deoD)
JDDGAC_24920 (yfiH)
Xanthine dehydrogenase:
hypoxanthine + NAD+ + H2O→xanthine + NADH + H+ (EC 1.17.1.4)
JDDGAC_12890 (paoB)
JDDGAC_12895 (paoC)
JDDGAC_23345 (xdhC)
JDDGAC_23350 (xdhB)
JDDGAC_23355 (xdhA)
Xanthine dehydrogenase:
xanthine + NAD+ + H2O→urate + NADH + H+ (EC 1.17.1.4)
JDDGAC_12890 (paoB)
JDDGAC_12895 (paoC)
JDDGAC_23345 (xdhC)
JDDGAC_23350 (xdhB)
JDDGAC_23355 (xdhA)

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information