MetaCyc Pathway: L-tyrosine degradation IV (to 4-methylphenol) in Escherichia coli ECRC98

Aspartate transaminase:
L-tyrosine + 2-oxoglutarate→3-(4-hydroxyphenyl)pyruvate + L-glutamate (EC 2.6.1.1; 2.6.1.27; 2.6.1.5; 2.6.1.57)

JDDGAC_04070 (ydcR)

JDDGAC_08995 (aspC)

JDDGAC_15045 (yjiR)

JDDGAC_16555 (tyrB)

JDDGAC_24515 (aRO8)

JDDGAC_28620 (hisC)

4-hydroxyphenylpyruvate oxidase:
2 3-(4-hydroxyphenyl)pyruvate + dioxygen→2 (4-hydroxyphenyl)acetate + 2 CO₂ (EC 1.2.3.13)

No genes

4-hydroxyphenylacetate decarboxylase:
(4-hydroxyphenyl)acetate + H⁺→4-methylphenol + CO₂ (EC 4.1.1.83)

No genes

Links:

Pathway details at MetaCyc
Fitness data for 6 genes
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All MetaCyc pathways for Escherichia coli ECRC98

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information