MetaCyc Pathway: anaerobic energy metabolism (invertebrates, mitochondrial) in Escherichia coli ECRC98

Add experiment(s):


Malate dehydrogenase (oxaloacetate-decarboxylating):
(S)-malate + NAD+→CO2 + pyruvate + NADH (EC 1.1.1.38)
JDDGAC_03850 (maeA)
Fumarate hydratase:
(S)-malate→fumarate + H2O (EC 4.2.1.2)
JDDGAC_01870 (fumD)
JDDGAC_02235 (fumB)
JDDGAC_02240 (fumC)
JDDGAC_10550 (ttdA)
JDDGAC_16160 (fumB)
JDDGAC_22980 (fumE)
pyruvate + coenzyme A + NAD+→CO2 + acetyl-CoA + NADH (EC 1.2.1.104)
JDDGAC_14085 (lpdA)
JDDGAC_14090 (aceF)
JDDGAC_14095 (aceE)
Succinate dehydrogenase (ubiquinone) (in reverse):
fumarate[in] + a rhodoquinol→succinate[in] + a rhodoquinone (EC 1.3.5.1)
No genes
acetyl-CoA + succinate→acetate + succinyl-CoA (EC 2.8.3.18)
No genes
succinate + propanoyl-CoA→succinyl-CoA + propanoate (EC 2.8.3.27)
No genes
Methylmalonyl-CoA mutase (in reverse):
succinyl-CoA→(R)-methylmalonyl-CoA (EC 5.4.99.2)
JDDGAC_23085 (scpA)
Succinate--CoA ligase (ADP-forming) (in reverse):
succinyl-CoA + ADP + phosphate→succinate + ATP + coenzyme A (EC 6.2.1.5)
JDDGAC_10565 (sucD)
JDDGAC_10570 (sucC)
Methylmalonyl-CoA epimerase:
(R)-methylmalonyl-CoA→(S)-methylmalonyl-CoA (EC 5.1.99.1)
No genes
Propionyl-CoA carboxylase (in reverse):
(S)-methylmalonyl-CoA + ADP + H+ + phosphate→propanoyl-CoA + ATP + hydrogen carbonate (EC 6.4.1.3)
JDDGAC_13725 (accA)
JDDGAC_26640 (accD)

Links:

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information