MetaCyc Pathway: guanosine ribonucleotides de novo biosynthesis in Escherichia coli ECRC98

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IMP dehydrogenase:
IMP + NAD+ + H2O→XMP + NADH + H+ (EC 1.1.1.205)
JDDGAC_25435 (guaB)
GMP synthase (glutamine-hydrolyzing):
XMP + ATP + L-glutamine + H2O→GMP + AMP + L-glutamate + diphosphate + 2 H+ (EC 6.3.5.2)
JDDGAC_25440 (guaA)
Guanylate kinase:
GMP + ATP→GDP + ADP (EC 2.7.4.8)
JDDGAC_16320 (phnN)
JDDGAC_19190 (gmk)
Nucleoside-diphosphate kinase:
GDP + ATP→GTP + ADP (EC 2.7.4.6)
JDDGAC_11795 (adk)
JDDGAC_25380 (ndk)

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information