MetaCyc Pathway: reductive monocarboxylic acid cycle in Escherichia coli ECRC98

Pyruvate synthase (in reverse):
acetyl-CoA + CO₂ + H⁺ + 2 a reduced ferredoxin [iron-sulfur] cluster→pyruvate + coenzyme A + 2 an oxidized ferredoxin [iron-sulfur] cluster (EC 1.2.7.1)

JDDGAC_04300 (nifJ)

Formate C-acetyltransferase (in reverse):
pyruvate + coenzyme A→acetyl-CoA + formate (EC 2.3.1.54)

JDDGAC_09120 (pflB)

JDDGAC_09325 (pflA)

JDDGAC_09770 (ybiY)

JDDGAC_09775

JDDGAC_09780 (pflD)

JDDGAC_17240 (pflC)

JDDGAC_17245 (pflD)

JDDGAC_22050 (tdcE)

JDDGAC_25010 (grcA)

Links:

Pathway details at MetaCyc
Fitness data for 10 genes
Select organism:
All MetaCyc pathways for Escherichia coli ECRC98

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information