MetaCyc Pathway: pyruvate fermentation to acetate II in Escherichia coli ECRC98

pyruvate + coenzyme A + NAD⁺→acetyl-CoA + CO₂ + NADH (EC 1.2.1.104)

JDDGAC_14085 (lpdA)

JDDGAC_14090 (aceF)

JDDGAC_14095 (aceE)

Phosphate acetyltransferase:
acetyl-CoA + phosphate→acetyl phosphate + coenzyme A (EC 2.3.1.8)

JDDGAC_25975 (pta)

JDDGAC_26755 (pta)

Acetate kinase (in reverse):
acetyl phosphate + ADP→acetate + ATP (EC 2.7.2.1; 2.7.2.15)

JDDGAC_00925 (purT)

JDDGAC_22045 (tdcD)

JDDGAC_25960 (eutP)

JDDGAC_25965 (eutQ)

JDDGAC_26760 (ackA)

Links:

Pathway details at MetaCyc
Fitness data for 10 genes
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All MetaCyc pathways for Escherichia coli ECRC98

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information