MetaCyc Pathway: L-isoleucine degradation II in Escherichia coli ECRC98

Add experiment(s):


Branched-chain-amino-acid transaminase:
L-isoleucine + 2-oxoglutarate→(3S)-3-methyl-2-oxopentanoate + L-glutamate
(EC 2.6.1.42)
JDDGAC_18265 (ilvE)
Branched-chain-2-oxoacid decarboxylase:
(3S)-3-methyl-2-oxopentanoate + H+→2-methylbutanal + CO2
(EC 4.1.1.72)
No genes
Alcohol dehydrogenase (in reverse):
2-methylbutanal + NADH + H+→2-methylbutanol + NAD+
(EC 1.1.1.1)
JDDGAC_03855 (adhP)
JDDGAC_05970 (adhE)
JDDGAC_12395 (frmA)
JDDGAC_12580 (yahK)
JDDGAC_15410 (ahr)
JDDGAC_19485 (yiaY)
JDDGAC_21340 (acuI)

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information