MetaCyc Pathway: formaldehyde assimilation III (dihydroxyacetone cycle) in Escherichia coli ECRC98

Add experiment(s):


Transketolase:
D-sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate→D-ribose 5-phosphate + D-xylulose 5-phosphate (EC 2.2.1.1)
JDDGAC_22955 (tkt)
JDDGAC_25940 (tkt)
Ribose-5-phosphate isomerase:
D-ribose 5-phosphate→D-ribulose 5-phosphate (EC 5.3.1.6)
JDDGAC_23095 (rpiA)
Ribulose-phosphate 3-epimerase:
D-ribulose 5-phosphate→D-xylulose 5-phosphate (EC 5.1.3.1)
JDDGAC_20760 (dam)
Formaldehyde transketolase:
D-xylulose 5-phosphate + formaldehyde→D-glyceraldehyde 3-phosphate + dihydroxyacetone (EC 2.2.1.3)
No genes
Glycerone kinase:
dihydroxyacetone + ATP→glycerone phosphate + ADP + H+ (EC 2.7.1.29)
No genes
Fructose-bisphosphate aldolase (in reverse):
glycerone phosphate + D-glyceraldehyde 3-phosphate→β-D-fructofuranose 1,6-bisphosphate (EC 4.1.2.13)
JDDGAC_16365 (fba)
JDDGAC_20120 (fba)
JDDGAC_23025 (fbaA)
JDDGAC_28215 (fbaB)
Triose-phosphate isomerase (in reverse):
glycerone phosphate→D-glyceraldehyde 3-phosphate (EC 5.3.1.1)
JDDGAC_17435 (tpiA)
Fructose-bisphosphatase:
β-D-fructofuranose 1,6-bisphosphate + H2O→β-D-fructofuranose 6-phosphate + phosphate (EC 3.1.3.11)
JDDGAC_10335 (ybhA)
JDDGAC_12280 (phoA)
JDDGAC_15585 (fbp)
JDDGAC_17405 (glpX)
JDDGAC_22975 (glpX)
Glyceraldehyde-3-phosphate dehydrogenase (phosphorylating):
D-glyceraldehyde 3-phosphate + NAD+ + phosphate→3-phospho-D-glyceroyl phosphate + NADH + H+ (EC 1.2.1.12)
JDDGAC_01305 (gapA)
JDDGAC_04185 (gap)
Transketolase (in reverse):
β-D-fructofuranose 6-phosphate + D-glyceraldehyde 3-phosphate→D-xylulose 5-phosphate + D-erythrose 4-phosphate (EC 2.2.1.1)
JDDGAC_22955 (tkt)
JDDGAC_25940 (tkt)
Phosphoglycerate kinase (in reverse):
3-phospho-D-glyceroyl phosphate + ADP→3-phospho-D-glycerate + ATP (EC 2.7.2.3)
JDDGAC_23020 (pgk)
Transaldolase (in reverse):
β-D-fructofuranose 6-phosphate + D-erythrose 4-phosphate→D-sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate (EC 2.2.1.2)
JDDGAC_09765 (fsa)
JDDGAC_14675
JDDGAC_17265 (fsa)
JDDGAC_25945 (tal)

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information