MetaCyc Pathway: Bifidobacterium shunt in Escherichia coli ECRC98

Add experiment(s):


Hexokinase:
D-glucopyranose + ATP→D-glucopyranose 6-phosphate + ADP + H+ (EC 2.7.1.1; 2.7.1.2)
JDDGAC_12220 (mak)
JDDGAC_26290 (glk)
Glucose-6-phosphate isomerase:
α-D-glucose 6-phosphate→β-D-fructofuranose 6-phosphate (EC 5.3.1.9)
JDDGAC_16800 (pgi)
JDDGAC_23585 (kduI)
Fructose-6-phosphate phosphoketolase:
β-D-fructofuranose 6-phosphate + phosphate→acetyl phosphate + D-erythrose 4-phosphate + H2O (EC 4.1.2.22)
No genes
Acetate kinase (in reverse):
acetyl phosphate + ADP→acetate + ATP (EC 2.7.2.1; 2.7.2.15)
JDDGAC_00925 (purT)
JDDGAC_22045 (tdcD)
JDDGAC_25960 (eutP)
JDDGAC_25965 (eutQ)
JDDGAC_26760 (ackA)
Transaldolase (in reverse):
D-erythrose 4-phosphate + β-D-fructofuranose 6-phosphate→D-sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate (EC 2.2.1.2)
JDDGAC_09765 (fsa)
JDDGAC_14675
JDDGAC_17265 (fsa)
JDDGAC_25945 (tal)
Transketolase:
D-sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate→D-ribose 5-phosphate + D-xylulose 5-phosphate (EC 2.2.1.1)
JDDGAC_22955 (tkt)
JDDGAC_25940 (tkt)
Ribose-5-phosphate isomerase:
D-ribose 5-phosphate→D-ribulose 5-phosphate (EC 5.3.1.6)
JDDGAC_23095 (rpiA)
Ribulose-phosphate 3-epimerase:
D-ribulose 5-phosphate→D-xylulose 5-phosphate (EC 5.1.3.1)
JDDGAC_20760 (dam)
Phosphoketolase:
D-xylulose 5-phosphate + phosphate→acetyl phosphate + D-glyceraldehyde 3-phosphate + H2O (EC 4.1.2.9)
No genes
Glyceraldehyde-3-phosphate dehydrogenase (phosphorylating):
D-glyceraldehyde 3-phosphate + NAD+ + phosphate→3-phospho-D-glyceroyl phosphate + NADH + H+ (EC 1.2.1.12)
JDDGAC_01305 (gapA)
JDDGAC_04185 (gap)
Phosphoglycerate kinase (in reverse):
3-phospho-D-glyceroyl phosphate + ADP→3-phospho-D-glycerate + ATP (EC 2.7.2.3)
JDDGAC_23020 (pgk)
3-phospho-D-glycerate→2-phospho-D-glycerate (EC 5.4.2.12)
JDDGAC_10390 (gpmA)
JDDGAC_14750
JDDGAC_19360 (gpmM)
Phosphopyruvate hydratase:
2-phospho-D-glycerate→phosphoenolpyruvate + H2O (EC 4.2.1.11)
JDDGAC_23940 (eno)
Pyruvate kinase (in reverse):
phosphoenolpyruvate + ADP + H+→pyruvate + ATP (EC 2.7.1.40)
JDDGAC_00895 (pyk)
JDDGAC_01865 (pykF)
L-lactate dehydrogenase (in reverse):
pyruvate + NADH + H+→(S)-lactate + NAD+ (EC 1.1.1.27)
JDDGAC_12750 (ykgF)
JDDGAC_12755 (ykgE)

Links:

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information