MetaCyc Pathway: glycolysis I (from glucose 6-phosphate) in Escherichia coli ECRC98

Add experiment(s):


D-glucopyranose[out] + an [HPr protein]-Nπ-phospho-L-histidine[in]→D-glucopyranose 6-phosphate[in] + an [HPr]-L-histidine[in] (EC 2.7.1.199)
JDDGAC_01095 (manZ)
JDDGAC_01100 (manY)
JDDGAC_01105 (manX)
JDDGAC_07195 (ptsG)
JDDGAC_16840 (manY)
JDDGAC_16845 (sorM)
JDDGAC_26135 (crr)
Glucose-6-phosphate isomerase:
α-D-glucose 6-phosphate→β-D-fructofuranose 6-phosphate (EC 5.3.1.9)
JDDGAC_16800 (pgi)
JDDGAC_23585 (kduI)
6-phosphofructokinase:
β-D-fructofuranose 6-phosphate + ATP→β-D-fructofuranose 1,6-bisphosphate + ADP + H+ (EC 2.7.1.11)
JDDGAC_01610 (pfkB)
JDDGAC_17455 (pfkA)
Fructose-bisphosphate aldolase:
β-D-fructofuranose 1,6-bisphosphate→glycerone phosphate + D-glyceraldehyde 3-phosphate (EC 4.1.2.13)
JDDGAC_16365 (fba)
JDDGAC_20120 (fba)
JDDGAC_23025 (fbaA)
JDDGAC_28215 (fbaB)
Fructose-bisphosphatase:
β-D-fructofuranose 1,6-bisphosphate + H2O→β-D-fructofuranose 6-phosphate + phosphate (EC 3.1.3.11)
JDDGAC_10335 (ybhA)
JDDGAC_12280 (phoA)
JDDGAC_15585 (fbp)
JDDGAC_17405 (glpX)
JDDGAC_22975 (glpX)
Triose-phosphate isomerase (in reverse):
glycerone phosphate→D-glyceraldehyde 3-phosphate (EC 5.3.1.1)
JDDGAC_17435 (tpiA)
Glyceraldehyde-3-phosphate dehydrogenase (phosphorylating):
D-glyceraldehyde 3-phosphate + NAD+ + phosphate→3-phospho-D-glyceroyl phosphate + NADH + H+ (EC 1.2.1.12)
JDDGAC_01305 (gapA)
JDDGAC_04185 (gap)
Phosphoglycerate kinase (in reverse):
3-phospho-D-glyceroyl phosphate + ADP→3-phospho-D-glycerate + ATP (EC 2.7.2.3)
JDDGAC_23020 (pgk)
3-phospho-D-glycerate→2-phospho-D-glycerate (EC 5.4.2.12)
JDDGAC_10390 (gpmA)
JDDGAC_14750
JDDGAC_19360 (gpmM)
3-phospho-D-glycerate→2-phospho-D-glycerate (EC 5.4.2.11)
JDDGAC_10390 (gpmA)
Phosphopyruvate hydratase:
2-phospho-D-glycerate→phosphoenolpyruvate + H2O (EC 4.2.1.11)
JDDGAC_23940 (eno)
Pyruvate kinase (in reverse):
phosphoenolpyruvate + ADP + H+→pyruvate + ATP (EC 2.7.1.40)
JDDGAC_00895 (pyk)
JDDGAC_01865 (pykF)
Pyruvate, water dikinase:
pyruvate + ATP + H2O→phosphoenolpyruvate + AMP + 2 H+ + phosphate (EC 2.7.9.2)
JDDGAC_01720 (ppsA)

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information