MetaCyc Pathway: superpathway of fatty acid biosynthesis initiation in Escherichia coli ECRC98

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[Acyl-carrier-protein] S-acetyltransferase:
acetyl-CoA + a soluble [acyl-carrier protein]→an acetyl-[acp] + coenzyme A (EC 2.3.1.38)
JDDGAC_07245 (fabH)
acetyl-CoA + a [carboxyl-carrier protein dimer]-N6-carboxybiotinyl-L-lysine→malonyl-CoA + a [biotin carboxyl-carrier-protein dimer]-N6-biotinyl-L-lysine (EC 2.1.3.15)
JDDGAC_13725 (accA)
JDDGAC_26640 (accD)
[Acyl-carrier-protein] S-malonyltransferase:
malonyl-CoA + a soluble [acyl-carrier protein]→a malonyl-[acp] + coenzyme A (EC 2.3.1.39)
JDDGAC_07240
JDDGAC_08010 (ymdE)
JDDGAC_08045 (fabB)
Beta-ketoacyl-acyl-carrier-protein synthase III:
acetyl-CoA + a malonyl-[acp] + H+→an acetoacetyl-[acp] + CO2 + coenzyme A (EC 2.3.1.180)
JDDGAC_07245 (fabH)
Beta-ketoacyl-acyl-carrier-protein synthase II:
an acetyl-[acp] + a malonyl-[acp] + H+→an acetoacetyl-[acp] + a soluble [acyl-carrier protein] + CO2 (EC 2.3.1.179; 2.3.1.41)
JDDGAC_07225 (fabF)
JDDGAC_20190 (fabB)
JDDGAC_20205 (fabB)
JDDGAC_26605 (fabB)

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information