MetaCyc Pathway: L-carnitine degradation I in Escherichia coli ECRC98

Add experiment(s):


L-carnitine[out] + γ-butyrobetaine[in]→L-carnitine[in] + γ-butyrobetaine[out]
JDDGAC_14495 (caiT)
L-carnitine + ATP + coenzyme A→(R)-carnitinyl-CoA + AMP + diphosphate (EC 6.2.1.48)
JDDGAC_14510 (caiC)
(R)-carnitinyl-CoA→crotonobetainyl-CoA + H2O (EC 4.2.1.149)
JDDGAC_14515 (caiD)
crotonobetainyl-CoA + a reduced electron-transfer flavoprotein→γ-butyrobetainyl-CoA + an oxidized electron-transfer flavoprotein + H+ (EC 1.3.8.13)
JDDGAC_14500 (caiA)
L-carnitine + γ-butyrobetainyl-CoA→(R)-carnitinyl-CoA + γ-butyrobetaine (EC 2.8.3.21)
JDDGAC_14505 (caiB)

Links:

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information