MetaCyc Pathway: glycolysis III (from glucose) in Escherichia coli ECRC98

Add experiment(s):


Hexokinase:
D-glucopyranose + ATP→D-glucopyranose 6-phosphate + ADP + H+ (EC 2.7.1.1; 2.7.1.2)
JDDGAC_12220 (mak)
JDDGAC_26290 (glk)
Glucose-6-phosphate isomerase:
α-D-glucose 6-phosphate→β-D-fructofuranose 6-phosphate (EC 5.3.1.9)
JDDGAC_16800 (pgi)
JDDGAC_23585 (kduI)
6-phosphofructokinase:
β-D-fructofuranose 6-phosphate + ATP→β-D-fructofuranose 1,6-bisphosphate + ADP + H+ (EC 2.7.1.11)
JDDGAC_01610 (pfkB)
JDDGAC_17455 (pfkA)
Fructose-bisphosphate aldolase:
β-D-fructofuranose 1,6-bisphosphate→glycerone phosphate + D-glyceraldehyde 3-phosphate (EC 4.1.2.13)
JDDGAC_16365 (fba)
JDDGAC_20120 (fba)
JDDGAC_23025 (fbaA)
JDDGAC_28215 (fbaB)
Triose-phosphate isomerase (in reverse):
glycerone phosphate→D-glyceraldehyde 3-phosphate (EC 5.3.1.1)
JDDGAC_17435 (tpiA)
Glyceraldehyde-3-phosphate dehydrogenase (phosphorylating):
D-glyceraldehyde 3-phosphate + NAD+ + phosphate→3-phospho-D-glyceroyl phosphate + NADH + H+ (EC 1.2.1.12)
JDDGAC_01305 (gapA)
JDDGAC_04185 (gap)
Phosphoglycerate kinase (in reverse):
3-phospho-D-glyceroyl phosphate + ADP→3-phospho-D-glycerate + ATP (EC 2.7.2.3)
JDDGAC_23020 (pgk)
3-phospho-D-glycerate→2-phospho-D-glycerate (EC 5.4.2.12)
JDDGAC_10390 (gpmA)
JDDGAC_14750
JDDGAC_19360 (gpmM)
3-phospho-D-glycerate→2-phospho-D-glycerate (EC 5.4.2.11)
JDDGAC_10390 (gpmA)
Phosphopyruvate hydratase:
2-phospho-D-glycerate→phosphoenolpyruvate + H2O (EC 4.2.1.11)
JDDGAC_23940 (eno)
Pyruvate kinase (in reverse):
phosphoenolpyruvate + ADP + H+→pyruvate + ATP (EC 2.7.1.40)
JDDGAC_00895 (pyk)
JDDGAC_01865 (pykF)

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information