MetaCyc Pathway: tRNA charging in Escherichia coli ECRC62

Add experiment(s):


Alanine--tRNA ligase:
a tRNAAla + L-alanine + ATP→an L-alanyl-[tRNAAla] + AMP + diphosphate (EC 6.1.1.7)
BNILDI_11115 (alaS)
Arginine--tRNA ligase:
L-arginine + a tRNAArg + ATP→an L-arginyl-[tRNAArg] + AMP + diphosphate (EC 6.1.1.19)
BNILDI_15420 (argS)
Asparagine--tRNA ligase:
L-asparagine + tRNAAsn + ATP→an L-asparaginyl-[tRNAAsn] + AMP + diphosphate (EC 6.1.1.22)
BNILDI_20185 (asnS)
Aspartate--tRNA ligase:
tRNAasp + L-aspartate + ATP→an L-aspartyl-[tRNAasp] + AMP + diphosphate (EC 6.1.1.12; 6.1.1.23)
BNILDI_15480 (aspS)
Cysteine--tRNA ligase:
L-cysteine + a tRNACys + ATP→an L-cysteinyl-[tRNACys] + AMP + diphosphate (EC 6.1.1.16)
BNILDI_22240 (cysS)
Glutamate--tRNA ligase:
L-glutamate + a tRNAglu + ATP→an L-glutamyl-[tRNAGlu] + AMP + diphosphate (EC 6.1.1.17)
BNILDI_12805 (gltX)
Glutamine--tRNA ligase:
L-glutamine + a tRNAGln + ATP→an L-glutaminyl-[tRNAGln] + AMP + diphosphate (EC 6.1.1.18)
BNILDI_21530 (glnS)
Glycine--tRNA ligase:
glycine + a tRNAGly + ATP→a glycyl-[tRNAGly] + AMP + diphosphate (EC 6.1.1.14)
BNILDI_03610 (glyS)
BNILDI_03615 (glyQ)
Histidine--tRNA ligase:
L-histidine + a tRNAHis + ATP→an L-histidyl-[tRNAHis] + AMP + diphosphate (EC 6.1.1.21)
BNILDI_12180 (hisS)
Isoleucine--tRNA ligase:
L-isoleucine + a tRNAIle + ATP→an L-isoleucyl-[tRNAIle] + AMP + diphosphate (EC 6.1.1.5)
BNILDI_08290 (ileS)
Leucine--tRNA ligase:
L-leucine + a tRNALeu + ATP→an L-leucyl-[tRNALeu] + AMP + diphosphate (EC 6.1.1.4)
BNILDI_21715 (leuS)
Lysine--tRNA ligase:
L-lysine + a tRNALys + ATP→an L-lysyl-[tRNALys] + AMP + diphosphate (EC 6.1.1.6)
BNILDI_06740 (lysS)
BNILDI_06890 (epmA)
BNILDI_10045 (lysS)
Methionine--tRNA ligase:
elongator tRNAMet + L-methionine + ATP→an L-methionyl-[elongator tRNAMet] + AMP + diphosphate (EC 6.1.1.10)
BNILDI_14255 (metG)
Phenylalanine--tRNA ligase:
L-phenylalanine + a tRNAPhe + ATP→an L-phenylalanyl-[tRNAPhe] + AMP + diphosphate (EC 6.1.1.20)
BNILDI_16395 (pheS)
BNILDI_16400 (pheT)
Proline--tRNA ligase:
L-proline + a tRNAPro + ATP→an L-prolyl-[tRNAPro] + AMP + diphosphate (EC 6.1.1.15)
BNILDI_09250 (proS)
Methionine--tRNA ligase:
L-methionine + initiator tRNAMet + ATP→an L-methionyl-[initiator tRNAMet] + AMP + diphosphate (EC 6.1.1.10)
BNILDI_14255 (metG)
Serine--tRNA ligase:
L-serine + a tRNAser + ATP→an L-seryl-[tRNAser] + AMP + diphosphate (EC 6.1.1.11)
BNILDI_20380 (serS)
Threonine--tRNA ligase:
L-threonine + a tRNAThr + ATP→an L-threonyl-[tRNAThr] + AMP + diphosphate (EC 6.1.1.3)
BNILDI_16370 (thrS)
Tryptophan--tRNA ligase:
L-tryptophan + a tRNATrp + ATP→an L-tryptophanyl-[tRNATrp] + AMP + diphosphate (EC 6.1.1.2)
BNILDI_02590 (gph)
Tyrosine--tRNA ligase:
L-tyrosine + a tRNATyr + ATP→an L-tyrosyl-[tRNATyr] + AMP + diphosphate (EC 6.1.1.1)
BNILDI_16810 (tyrS)
Valine--tRNA ligase:
L-valine + a tRNAVal + ATP→an L-valyl-[tRNAVal] + AMP + diphosphate (EC 6.1.1.9)
BNILDI_07445 (valS)

Links:

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information