MetaCyc Pathway: adenosine nucleotides degradation II in Escherichia coli ECRC62

Add experiment(s):


5'-nucleotidase:
AMP + H2O→adenosine + phosphate (EC 3.1.3.5)
BNILDI_06365 (aphA)
BNILDI_07995 (yjjG)
BNILDI_10845 (surE)
BNILDI_13360 (yfbR)
BNILDI_22460 (ushA)
BNILDI_22965 (phoA)
Adenosine deaminase:
adenosine + H+ + H2O→inosine + ammonium (EC 3.5.4.4)
BNILDI_11735 (yfiH)
BNILDI_16885 (add)
Purine-nucleoside phosphorylase:
inosine + phosphate→hypoxanthine + α-D-ribose-1-phosphate (EC 2.4.2.1)
BNILDI_08050 (deoD)
BNILDI_11735 (yfiH)
BNILDI_22925 (ppnP)
Xanthine dehydrogenase:
hypoxanthine + NAD+ + H2O→xanthine + NADH + H+ (EC 1.17.1.4)
BNILDI_00140 (paoB)
BNILDI_00145 (paoC)
BNILDI_10155 (xdhC)
BNILDI_10160 (xdhB)
BNILDI_10165 (xdhA)
Xanthine dehydrogenase:
xanthine + NAD+ + H2O→urate + NADH + H+ (EC 1.17.1.4)
BNILDI_00140 (paoB)
BNILDI_00145 (paoC)
BNILDI_10155 (xdhC)
BNILDI_10160 (xdhB)
BNILDI_10165 (xdhA)

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information