MetaCyc Pathway: superpathway of pyrimidine deoxyribonucleosides degradation in Escherichia coli ECRC62

Add experiment(s):


Cytidine deaminase:
2'-deoxycytidine + H+ + H2O→2'-deoxyuridine + ammonium (EC 3.5.4.5)
BNILDI_14060 (cdd)
Pyrimidine-nucleoside phosphorylase:
thymidine + phosphate→2-deoxy-α-D-ribose 1-phosphate + thymine (EC 2.4.2.2; 2.4.2.4)
BNILDI_08040 (deoA)
BNILDI_22925 (ppnP)
Pyrimidine-nucleoside phosphorylase:
2'-deoxyuridine + phosphate→2-deoxy-α-D-ribose 1-phosphate + uracil (EC 2.4.2.2; 2.4.2.3)
BNILDI_05085 (udp)
BNILDI_08040 (deoA)
BNILDI_08050 (deoD)
Phosphopentomutase:
2-deoxy-α-D-ribose 1-phosphate→2-deoxy-D-ribose 5-phosphate (EC 5.4.2.7)
BNILDI_02570 (yhfW)
BNILDI_08045 (deoB)
Deoxyribose-phosphate aldolase:
2-deoxy-D-ribose 5-phosphate→acetaldehyde + D-glyceraldehyde 3-phosphate (EC 4.1.2.4)
BNILDI_08035 (deoC)
Acetaldehyde dehydrogenase (acetylating):
acetaldehyde + coenzyme A + NAD+→acetyl-CoA + NADH + H+ (EC 1.2.1.10)
BNILDI_12535 (eutE)
BNILDI_18590 (adhE)
BNILDI_23090 (mhpF)

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information