MetaCyc Pathway: superpathway of anaerobic sucrose degradation in Escherichia coli ECRC62

Add experiment(s):


Sucrose synthase (in reverse):
sucrose + H+ + UDP→β-D-fructofuranose + UDP-α-D-glucose (EC 2.4.1.13)
No genes
Fructokinase:
β-D-fructofuranose + ATP→β-D-fructofuranose 6-phosphate + ADP + H+ (EC 2.7.1.4)
BNILDI_05375 (yihV)
BNILDI_13005 (cscK)
BNILDI_22910 (mak)
UTP-monosaccharide-1-phosphate uridylyltransferase (in reverse):
UDP-α-D-glucose + diphosphate→α-D-glucopyranose 1-phosphate + H+ + UTP (EC 2.7.7.64; 2.7.7.9)
BNILDI_14655 (galF)
BNILDI_18615 (galU)
6-phosphofructokinase:
β-D-fructofuranose 6-phosphate + ATP→β-D-fructofuranose 1,6-bisphosphate + ADP + H+ (EC 2.7.1.11)
BNILDI_05565 (pfkA)
BNILDI_16340 (pfkB)
Phosphoglucomutase:
α-D-glucopyranose 1-phosphate→D-glucopyranose 6-phosphate (EC 5.4.2.2)
BNILDI_01665 (glmM)
BNILDI_21485 (pgm)
Fructose-bisphosphate aldolase:
β-D-fructofuranose 1,6-bisphosphate→glycerone phosphate + D-glyceraldehyde 3-phosphate (EC 4.1.2.13)
BNILDI_03130 (fba)
BNILDI_09845 (fbaA)
BNILDI_14360 (fbaB)
Fructose-bisphosphatase:
β-D-fructofuranose 1,6-bisphosphate + H2O→β-D-fructofuranose 6-phosphate + phosphate (EC 3.1.3.11)
BNILDI_05615 (glpX)
BNILDI_07310 (fbp)
BNILDI_09795 (glpX)
BNILDI_21105 (ybhA)
BNILDI_22965 (phoA)
Glucose-6-phosphate isomerase:
α-D-glucose 6-phosphate→β-D-fructofuranose 6-phosphate (EC 5.3.1.9)
BNILDI_06185 (pgi)
BNILDI_10285 (kduI)
Triose-phosphate isomerase (in reverse):
glycerone phosphate→D-glyceraldehyde 3-phosphate (EC 5.3.1.1)
BNILDI_05585 (tpiA)
Glyceraldehyde-3-phosphate dehydrogenase (phosphorylating):
D-glyceraldehyde 3-phosphate + NAD+ + phosphate→3-phospho-D-glyceroyl phosphate + NADH + H+ (EC 1.2.1.12)
BNILDI_16045 (gapA)
BNILDI_17830 (gap)
Phosphoglycerate kinase (in reverse):
3-phospho-D-glyceroyl phosphate + ADP→3-phospho-D-glycerate + ATP (EC 2.7.2.3)
BNILDI_09840 (pgk)
3-phospho-D-glycerate→2-phospho-D-glycerate (EC 5.4.2.12)
BNILDI_03900 (gpmM)
BNILDI_08115
BNILDI_21160 (gpmA)
3-phospho-D-glycerate→2-phospho-D-glycerate (EC 5.4.2.11)
BNILDI_21160 (gpmA)
Phosphopyruvate hydratase:
2-phospho-D-glycerate→phosphoenolpyruvate + H2O (EC 4.2.1.11)
BNILDI_10655 (eno)
Pyruvate kinase (in reverse):
phosphoenolpyruvate + ADP + H+→pyruvate + ATP (EC 2.7.1.40)
BNILDI_15630 (pyk)
BNILDI_16600 (pykF)
L-lactate dehydrogenase (in reverse):
pyruvate + NADH + H+→(S)-lactate + NAD+ (EC 1.1.1.27)
BNILDI_00040 (ykgF)
BNILDI_00045 (ykgE)
Pyruvate, water dikinase:
pyruvate + ATP + H2O→phosphoenolpyruvate + AMP + 2 H+ + phosphate (EC 2.7.9.2)
BNILDI_16455 (ppsA)
Pyruvate decarboxylase:
pyruvate + H+→acetaldehyde + CO2 (EC 4.1.1.1)
No genes
Alcohol dehydrogenase (in reverse):
acetaldehyde + NADH + H+→ethanol + NAD+ (EC 1.1.1.1)
BNILDI_02020 (acuI)
BNILDI_03780 (yiaY)
BNILDI_07480 (ahr)
BNILDI_17525 (adhP)
BNILDI_18590 (adhE)
BNILDI_23065 (frmA)

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information