MetaCyc Pathway: superpathway of glucose and xylose degradation in Escherichia coli ECRC62

Add experiment(s):


Glucose-6-phosphate dehydrogenase:
D-glucopyranose 6-phosphate + NADP+→6-phospho D-glucono-1,5-lactone + NADPH + H+ (EC 1.1.1.49)
BNILDI_15640 (zwf)
Xylose isomerase:
α-D-xylopyranose→α-D-xylulofuranose (EC 5.3.1.5)
BNILDI_03645 (xylA)
6-phosphogluconolactonase:
6-phospho D-glucono-1,5-lactone + H2O→D-gluconate 6-phosphate + H+ (EC 3.1.1.31)
BNILDI_21100 (pgl)
Xylulokinase:
D-xylulose + ATP→D-xylulose 5-phosphate + ADP + H+ (EC 2.7.1.17)
BNILDI_03640 (xylB)
Phosphogluconate dehydrogenase (decarboxylating):
D-gluconate 6-phosphate + NADP+→D-ribulose 5-phosphate + CO2 + NADPH (EC 1.1.1.44)
BNILDI_14695 (gndA)
Ribose-5-phosphate isomerase (in reverse):
D-ribulose 5-phosphate→D-ribose 5-phosphate (EC 5.3.1.6)
BNILDI_06530
BNILDI_09900 (rpiA)
Ribulose-phosphate 3-epimerase:
D-ribulose 5-phosphate→D-xylulose 5-phosphate (EC 5.1.3.1)
BNILDI_02600 (dam)
Transketolase (in reverse):
D-ribose 5-phosphate + D-xylulose 5-phosphate→D-sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate (EC 2.2.1.1)
BNILDI_09775 (tkt)
BNILDI_12485 (tkt)
Transaldolase:
D-sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate→D-erythrose 4-phosphate + β-D-fructofuranose 6-phosphate (EC 2.2.1.2)
BNILDI_05750 (fsa)
BNILDI_08195
BNILDI_12490 (tal)
BNILDI_20760 (fsa)
Transketolase:
D-erythrose 4-phosphate + D-xylulose 5-phosphate→β-D-fructofuranose 6-phosphate + D-glyceraldehyde 3-phosphate (EC 2.2.1.1)
BNILDI_09775 (tkt)
BNILDI_12485 (tkt)
Glyceraldehyde-3-phosphate dehydrogenase (phosphorylating):
D-glyceraldehyde 3-phosphate + NAD+ + phosphate→3-phospho-D-glyceroyl phosphate + NADH + H+ (EC 1.2.1.12)
BNILDI_16045 (gapA)
BNILDI_17830 (gap)
Phosphoglycerate kinase (in reverse):
3-phospho-D-glyceroyl phosphate + ADP→3-phospho-D-glycerate + ATP (EC 2.7.2.3)
BNILDI_09840 (pgk)
3-phospho-D-glycerate→2-phospho-D-glycerate (EC 5.4.2.12)
BNILDI_03900 (gpmM)
BNILDI_08115
BNILDI_21160 (gpmA)
Phosphopyruvate hydratase:
2-phospho-D-glycerate→phosphoenolpyruvate + H2O (EC 4.2.1.11)
BNILDI_10655 (eno)
Pyruvate kinase (in reverse):
phosphoenolpyruvate + ADP + H+→pyruvate + ATP (EC 2.7.1.40)
BNILDI_15630 (pyk)
BNILDI_16600 (pykF)
D-lactate dehydrogenase (in reverse):
pyruvate + NADH + H+→(R)-lactate + NAD+ (EC 1.1.1.28)
BNILDI_14140 (dld)
BNILDI_17985 (ldhA)
L-lactate dehydrogenase (in reverse):
pyruvate + NADH + H+→(S)-lactate + NAD+ (EC 1.1.1.27)
BNILDI_00040 (ykgF)
BNILDI_00045 (ykgE)

Links:

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information