MetaCyc Pathway: superpathway of sulfate assimilation and cysteine biosynthesis in Escherichia coli ECRC102

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Phosphoglycerate dehydrogenase:
3-phospho-D-glycerate + NAD+→3-phosphooxypyruvate + NADH + H+ (EC 1.1.1.95)
NIAGMN_17225 (serA)
NIAGMN_23950 (ghrA)
Sulfate adenylyltransferase:
sulfate + ATP + H+→adenosine 5'-phosphosulfate + diphosphate (EC 2.7.7.4)
NIAGMN_18210 (cysD)
NIAGMN_18215 (cysN)
Adenylyl-sulfate kinase:
adenosine 5'-phosphosulfate + ATP→3'-phosphoadenylyl-sulfate + ADP + H+ (EC 2.7.1.25)
NIAGMN_18220 (cysC)
Phosphoserine transaminase (in reverse):
3-phosphooxypyruvate + L-glutamate→O-phospho-L-serine + 2-oxoglutarate (EC 2.6.1.52)
NIAGMN_03210 (serC)
Phosphoadenylyl-sulfate reductase (thioredoxin) (in reverse):
3'-phosphoadenylyl-sulfate + a reduced thioredoxin→sulfite + adenosine 3',5'-bisphosphate + an oxidized thioredoxin + 2 H+ (EC 1.8.4.8)
NIAGMN_18150 (cysH)
Phosphoserine phosphatase:
O-phospho-L-serine + H2O→L-serine + phosphate (EC 3.1.3.3)
NIAGMN_06680 (phoA)
NIAGMN_09050 (serB)
NIAGMN_10755 (aphA)
Serine O-acetyltransferase:
L-serine + acetyl-CoA→O-acetyl-L-serine + coenzyme A (EC 2.3.1.30)
NIAGMN_02160 (cysE)
NIAGMN_13520 (cysE)
Sulfite reductase (NADPH) (in reverse):
sulfite + 3 NADPH + 5 H+→hydrogen sulfide + 3 NADP+ + 3 H2O (EC 1.8.1.2)
NIAGMN_18140 (cysJ)
NIAGMN_18145 (cysI)
Cysteine synthase:
O-acetyl-L-serine + hydrogen sulfide→L-cysteine + acetate + H+ (EC 2.5.1.47)
NIAGMN_19940 (cysM)
NIAGMN_19970 (cysK)

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information