MetaCyc Pathway: adenosine nucleotides degradation II in Escherichia coli ECRC101

Add experiment(s):


5'-nucleotidase:
AMP + H2O→adenosine + phosphate (EC 3.1.3.5)
MCAODC_01800 (yjjG)
MCAODC_03420 (aphA)
MCAODC_11005 (surE)
MCAODC_13860 (yfbR)
MCAODC_27330 (ushA)
MCAODC_27850 (phoA)
Adenosine deaminase:
adenosine + H+ + H2O→inosine + ammonium (EC 3.5.4.4)
MCAODC_11785 (yfiH)
MCAODC_17830 (add)
Purine-nucleoside phosphorylase:
inosine + phosphate→hypoxanthine + α-D-ribose-1-phosphate (EC 2.4.2.1)
MCAODC_01730 (deoD)
MCAODC_11785 (yfiH)
MCAODC_27810 (ppnP)
Xanthine dehydrogenase:
hypoxanthine + NAD+ + H2O→xanthine + NADH + H+ (EC 1.17.1.4)
MCAODC_10225 (xdhC)
MCAODC_10230 (xdhB)
MCAODC_10235 (xdhA)
MCAODC_28465 (paoB)
MCAODC_28470 (paoC)
Xanthine dehydrogenase:
xanthine + NAD+ + H2O→urate + NADH + H+ (EC 1.17.1.4)
MCAODC_10225 (xdhC)
MCAODC_10230 (xdhB)
MCAODC_10235 (xdhA)
MCAODC_28465 (paoB)
MCAODC_28470 (paoC)

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information