MetaCyc Pathway: superpathway of fermentation (Chlamydomonas reinhardtii) in Escherichia coli ECRC101

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Formate C-acetyltransferase (in reverse):
pyruvate + coenzyme A→acetyl-CoA + formate (EC 2.3.1.54)
MCAODC_04115 (pflC)
MCAODC_04120 (pflD)
MCAODC_08930 (tdcE)
MCAODC_11875 (grcA)
MCAODC_24900 (pflB)
MCAODC_24905 (pflA)
MCAODC_25350 (ybiY)
MCAODC_25355
MCAODC_25360 (pflD)
Pyruvate decarboxylase:
pyruvate + H+→acetaldehyde + CO2 (EC 4.1.1.1)
No genes
Acetaldehyde dehydrogenase (acetylating) (in reverse):
acetyl-CoA + NADH + H+→acetaldehyde + coenzyme A + NAD+ (EC 1.2.1.10)
MCAODC_12575 (eutE)
MCAODC_21655 (adhE)
MCAODC_27995 (mhpF)
Pyruvate synthase:
pyruvate + coenzyme A + 2 an oxidized ferredoxin [iron-sulfur] cluster→acetyl-CoA + CO2 + H+ + 2 a reduced ferredoxin [iron-sulfur] cluster (EC 1.2.7.1)
MCAODC_16125 (nifJ)
Alcohol dehydrogenase (in reverse):
acetaldehyde + NADH + H+→ethanol + NAD+ (EC 1.1.1.1)
MCAODC_02275 (ahr)
MCAODC_06370 (yiaY)
MCAODC_08235 (acuI)
MCAODC_16575 (adhP)
MCAODC_21655 (adhE)
MCAODC_27970 (frmA)
MCAODC_28155 (yahK)
D-lactate dehydrogenase (in reverse):
pyruvate + NADH + H+→(R)-lactate + NAD+ (EC 1.1.1.28)
MCAODC_14700 (dld)
MCAODC_16140 (ldhA)
Ferredoxin hydrogenase (in reverse):
2 a reduced ferredoxin [iron-sulfur] cluster + 2 H+→H2 + 2 an oxidized ferredoxin [iron-sulfur] cluster (EC 1.12.7.2)
MCAODC_11100 (hycB)
MCAODC_11105 (hycC)
MCAODC_11110 (hycD)
MCAODC_11115 (hycE)
MCAODC_11120 (hycF)
MCAODC_11125 (hycG)
MCAODC_12400 (hyfG)
MCAODC_12420 (hyfC)
Phosphate acetyltransferase:
acetyl-CoA + phosphate→acetyl phosphate + coenzyme A (EC 2.3.1.8)
MCAODC_12560 (pta)
MCAODC_13830 (pta)
Acetate kinase (in reverse):
acetyl phosphate + ADP→acetate + ATP (EC 2.7.2.1; 2.7.2.15)
MCAODC_08925 (tdcD)
MCAODC_12545 (eutP)
MCAODC_12550 (eutQ)
MCAODC_13835 (ackA)
MCAODC_19055 (purT)

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information