MetaCyc Pathway: L-phenylalanine biosynthesis I in Escherichia coli ECRC101

Chorismate mutase:
chorismate→prephenate (EC 5.4.99.5)

Prephenate dehydratase:
prephenate + H⁺→3-phenyl-2-oxopropanoate + CO₂ + H₂O (EC 4.2.1.51)

Aspartate transaminase (in reverse):
3-phenyl-2-oxopropanoate + L-glutamate→L-phenylalanine + 2-oxoglutarate (EC 2.6.1.1; 2.6.1.27; 2.6.1.57)

MCAODC_01965 (yjiR)

MCAODC_03430 (tyrB)

MCAODC_05150 (ilvE)

MCAODC_11375 (aRO8)

MCAODC_16360 (ydcR)

MCAODC_20430 (hisC)

MCAODC_24775 (aspC)

Links:

Pathway details at MetaCyc
Fitness data for 9 genes
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All MetaCyc pathways for Escherichia coli ECRC101

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information