MetaCyc Pathway: superpathway of purines degradation in plants in Escherichia coli ECRC101

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Adenosine-phosphate deaminase:
AMP + H+ + H2O→IMP + ammonium (EC 3.5.4.17; 3.5.4.6)
No genes
5'-nucleotidase:
GMP + H2O→guanosine + phosphate (EC 3.1.3.5)
MCAODC_01800 (yjjG)
MCAODC_03420 (aphA)
MCAODC_07595 (yrfG)
MCAODC_11005 (surE)
MCAODC_13860 (yfbR)
MCAODC_27330 (ushA)
Guanosine deaminase:
guanosine + H+ + H2O→xanthosine + ammonium (EC 3.5.4.15)
No genes
IMP dehydrogenase:
IMP + NAD+ + H2O→XMP + NADH + H+ (EC 1.1.1.205)
MCAODC_12290 (guaB)
5'-nucleotidase:
IMP + H2O→inosine + phosphate (EC 3.1.3.5; 3.1.3.99)
MCAODC_01800 (yjjG)
MCAODC_03420 (aphA)
MCAODC_07595 (yrfG)
MCAODC_11005 (surE)
MCAODC_13860 (yfbR)
MCAODC_27330 (ushA)
MCAODC_27850 (phoA)
Purine nucleosidase:
guanosine + H2O→guanine + D-ribofuranose (EC 3.2.2.1)
MCAODC_01475 (rihC)
MCAODC_14520 (rihB)
MCAODC_26490 (rihA)
Guanine deaminase:
guanine + H+ + H2O→xanthine + ammonium (EC 3.5.4.3)
MCAODC_10150 (guaD)
Inosine nucleosidase:
inosine + H2O→hypoxanthine + D-ribofuranose (EC 3.2.2.2)
MCAODC_01475 (rihC)
MCAODC_14520 (rihB)
MCAODC_26490 (rihA)
5'-nucleotidase:
XMP + H2O→xanthosine + phosphate (EC 3.1.3.5)
MCAODC_01800 (yjjG)
MCAODC_03420 (aphA)
MCAODC_11005 (surE)
MCAODC_13860 (yfbR)
MCAODC_27330 (ushA)
Xanthine dehydrogenase:
hypoxanthine + NAD+ + H2O→xanthine + NADH + H+ (EC 1.17.1.4)
MCAODC_10225 (xdhC)
MCAODC_10230 (xdhB)
MCAODC_10235 (xdhA)
MCAODC_28465 (paoB)
MCAODC_28470 (paoC)
Purine nucleosidase:
xanthosine + H2O→xanthine + D-ribofuranose (EC 3.2.2.1)
MCAODC_01475 (rihC)
MCAODC_14520 (rihB)
MCAODC_26490 (rihA)
Xanthine dehydrogenase:
xanthine + NAD+ + H2O→urate + NADH + H+ (EC 1.17.1.4)
MCAODC_10225 (xdhC)
MCAODC_10230 (xdhB)
MCAODC_10235 (xdhA)
MCAODC_28465 (paoB)
MCAODC_28470 (paoC)
Urate oxidase:
urate + dioxygen + H2O→(S)-5-hydroxyisourate + hydrogen peroxide (EC 1.7.3.3)
No genes
Hydroxyisourate hydrolase:
(S)-5-hydroxyisourate + H2O→(S)-2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline + H+ (EC 3.5.2.17)
MCAODC_19835 (hiuH)
(S)-2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline + H+→(S)-(+)-allantoin + CO2 (EC 4.1.1.97)
No genes
Allantoinase:
(S)-(+)-allantoin + H2O→allantoate + H+ (EC 3.5.2.5)
MCAODC_27115 (allB)
MCAODC_27120 (allB)
Allantoicase:
allantoate + H2O→(S)-ureidoglycolate + urea (EC 3.5.3.4)
No genes
Ureidoglycolate lyase:
(S)-ureidoglycolate→glyoxylate + urea (EC 4.3.2.3)
MCAODC_27150 (allA)

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information