MetaCyc Pathway: 3-phenylpropanoate and 3-(3-hydroxyphenyl)propanoate degradation to 2-hydroxypentadienoate in Escherichia coli ECRC101

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3-phenylpropanoate dioxygenase:
3-phenylpropanoate + NADH + dioxygen + H+→3-(5,6-dihydroxycyclohexa-1,3-dien-1-yl)propanoate + NAD+
(EC 1.14.12.19)
MCAODC_12090 (hcaD)
MCAODC_12100 (hcaC)
MCAODC_12105 (hcaF)
MCAODC_12110 (hcaE)
3-(3-hydroxyphenyl)propanoate + NADH + dioxygen + H+→3-(2,3-dihydroxyphenyl)propanoate + NAD+ + H2O (EC 1.14.13.127)
MCAODC_28015 (mhpA)
3-(5,6-dihydroxycyclohexa-1,3-dien-1-yl)propanoate + NAD+→3-(2,3-dihydroxyphenyl)propanoate + NADH + H+ (EC 1.3.1.87)
MCAODC_12095 (hcaB)
3-carboxyethylcatechol 2,3-dioxygenase:
3-(2,3-dihydroxyphenyl)propanoate + dioxygen→(2Z,4E)-2-hydroxy-6-oxonona-2,4-diene-1,9-dioate + H+
(EC 1.13.11.16)
MCAODC_28010 (mhpB)
(2Z,4E)-2-hydroxy-6-oxonona-2,4-diene-1,9-dioate + H2O→(2Z)-2-hydroxypenta-2,4-dienoate + H+ + succinate (EC 3.7.1.14)
MCAODC_28005 (mhpC)

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information