MetaCyc Pathway: cyanate degradation in Escherichia coli ECRC101

Cyanase:
cyanate + hydrogen carbonate + H⁺→carbamate + CO₂ (EC 4.2.1.104)

MCAODC_28060 (cynS)

carbamate + 2 H⁺→CO₂ + ammonium (spontaneous) (EC 3.5.1.110; 3.5.1.20; 3.5.1.54; 4.2.1.104)

MCAODC_26220 (pxpC)

MCAODC_26225 (pxpB)

MCAODC_28060 (cynS)

Carbonate dehydratase (in reverse):
CO₂ + H₂O→hydrogen carbonate + H⁺ (EC 4.2.1.1)

MCAODC_00955 (can)

MCAODC_28065 (cynT)

Links:

Pathway details at MetaCyc
Fitness data for 5 genes
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All MetaCyc pathways for Escherichia coli ECRC101

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information