MetaCyc Pathway: L-serine biosynthesis I in Escherichia coli ECRC101

Phosphoglycerate dehydrogenase:
3-phospho-D-glycerate + NAD⁺→3-phosphooxypyruvate + NADH + H⁺ (EC 1.1.1.95)

OKFHMN_19460 (serA)

Phosphoserine transaminase (in reverse):
3-phosphooxypyruvate + L-glutamate→O-phospho-L-serine + 2-oxoglutarate (EC 2.6.1.52)

OKFHMN_05490 (serC)

Phosphoserine phosphatase:
O-phospho-L-serine + H₂O→L-serine + phosphate (EC 3.1.3.3)

OKFHMN_08625 (phoA)

OKFHMN_11200 (serB)

OKFHMN_12910 (aphA)

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Pathway details at MetaCyc
Fitness data for 6 genes
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All MetaCyc pathways for Escherichia coli ECRC101

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information