MetaCyc Pathway: TCA cycle VIII (Chlamydia) in Escherichia coli ECOR38

Add experiment(s):


2-oxoglutarate + coenzyme A + NAD+→succinyl-CoA + CO2 + NADH (EC 1.2.1.105)
HEPCGN_08470 (lpdA)
Succinate--CoA ligase (ADP-forming) (in reverse):
succinyl-CoA + ADP + phosphate→succinate + ATP + coenzyme A (EC 6.2.1.5)
HEPCGN_01315 (sucC)
HEPCGN_01320 (sucD)
Succinate dehydrogenase (ubiquinone):
succinate[in] + an electron-transfer quinone→fumarate[in] + an electron-transfer quinol (EC 1.3.5.1)
No genes
Fumarate hydratase (in reverse):
fumarate + H2O→(S)-malate (EC 4.2.1.2)
HEPCGN_01375 (ttdA)
HEPCGN_05680 (fumD)
HEPCGN_06020 (fumB)
HEPCGN_06025 (fumC)
HEPCGN_11160 (fumB)
HEPCGN_18660 (fumE)
Malate dehydrogenase:
(S)-malate + NAD+→oxaloacetate + NADH + H+ (EC 1.1.1.37; 1.1.1.38)
HEPCGN_01775 (hcxB)
HEPCGN_16660 (mdh)
HEPCGN_26435 (maeA)
Aspartate transaminase (in reverse):
oxaloacetate + L-glutamate→2-oxoglutarate + L-aspartate (EC 2.6.1.1)
HEPCGN_14250
HEPCGN_20050 (aRO8)
HEPCGN_23140 (aspC)
HEPCGN_26230 (ydcR)

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information