MetaCyc Pathway: glycine degradation in Escherichia coli ECOR38

Add experiment(s):


glycine + NAD+ + a tetrahydrofolate→ammonium + a 5,10-methylenetetrahydrofolate + CO2 + NADH (EC 1.4.1.27)
HEPCGN_08470 (lpdA)
HEPCGN_18810 (gcvT)
Glycine hydroxymethyltransferase (in reverse):
glycine + a 5,10-methylenetetrahydrofolate + H2O→L-serine + a tetrahydrofolate (EC 2.1.2.1)
HEPCGN_20655 (glyA)
L-serine ammonia-lyase:
L-serine→ammonium + pyruvate (EC 4.3.1.17)
HEPCGN_04940 (sdaA)
HEPCGN_17235 (tdcB)
HEPCGN_17260 (tdcG)
HEPCGN_19430 (sdaB)

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information