Peptidoglycan glycosyltransferase:
Und-PP-[β-D-GlcNAc-(1→4)]-MurNAc-L-Ala-γ-D-Glu-meso-DAP-D-Ala-D-Ala + a nascent peptidoglycan with (L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine) pentapeptide→a nascent peptidoglycan with (L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine) pentapeptide + di-trans,octa-cis-undecaprenyl diphosphate (EC 2.4.1.129) |
| HEPCGN_00905 (mrdB) |
| HEPCGN_08275 (mrcB) |
| HEPCGN_08620 (ftsW) |
| HEPCGN_08645 (ftsI) |
| HEPCGN_15900 (mrcA) |
| HEPCGN_16785 (mtgA) |
| HEPCGN_20820 (pbpC) |
Serine-type D-Ala-D-Ala carboxypeptidase:
a nascent peptidoglycan with (L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine) pentapeptide + H2O→a nascent peptidoglycan with (L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanine) tetrapeptide + D-alanine (EC 3.4.16.4) |
| HEPCGN_00895 (dacA) |
| HEPCGN_01990 (dacC) |
| HEPCGN_03275 (dacD) |
| HEPCGN_07305 (ampH) |
| HEPCGN_08275 (mrcB) |
| HEPCGN_15900 (mrcA) |
| HEPCGN_16915 (dacB) |
| HEPCGN_21300 (pbp4b) |
Serine-type D-Ala-D-Ala carboxypeptidase:
a nascent peptidoglycan with (L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine) pentapeptide + a peptidoglycan internal segment with (L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanine) tetrapeptide→a nascent peptidoglycan with D,D cross-links (meso-diaminopimelate containing) + D-alanine (EC 3.4.16.4) |
| HEPCGN_00895 (dacA) |
| HEPCGN_00910 (mrdA) |
| HEPCGN_01990 (dacC) |
| HEPCGN_03275 (dacD) |
| HEPCGN_08275 (mrcB) |
| HEPCGN_08645 (ftsI) |
| HEPCGN_15900 (mrcA) |
| HEPCGN_16915 (dacB) |
| a nascent peptidoglycan with (L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine) pentapeptide→a mature peptidoglycan with (L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine) pentapeptide + H+ + di-trans,octa-cis-undecaprenyl diphosphate |
| No genes |
| a nascent peptidoglycan with (L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanine) tetrapeptide + a peptidoglycan internal segment with (L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanine) tetrapeptide→a nascent peptidoglycan with L,D cross links (meso-diaminopimelate containing) + D-alanine |
| HEPCGN_05665 (ldtE) |
| HEPCGN_23125 (ldtD) |
Muramoyltetrapeptide carboxypeptidase:
a nascent peptidoglycan with (L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanine) tetrapeptide + H2O→a nascent peptidoglycan with (L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimelate) tripeptide + D-alanine (EC 3.4.17.13) |
| HEPCGN_05795 (mepH) |
| HEPCGN_22665 (mepS) |
| HEPCGN_23125 (ldtD) |
| HEPCGN_24800 (ldcA) |
| a nascent peptidoglycan with (L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanine) tetrapeptide + glycine→a nascent peptidoglycan with (L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimeloyl-glycine) tetrapeptide + D-alanine |
| HEPCGN_23125 (ldtD) |
| a nascent peptidoglycan with (L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanine) tetrapeptide→a mature peptidoglycan (with L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanine tetrapeptide) + H+ + di-trans,octa-cis-undecaprenyl diphosphate |
| No genes |
| a nascent peptidoglycan with D,D cross-links (meso-diaminopimelate containing)→a mature peptidoglycan with D,D cross-links (meso-diaminopimelate containing) + H+ + di-trans,octa-cis-undecaprenyl diphosphate |
| No genes |
| a nascent peptidoglycan with (L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimelate) tripeptide→a mature peptidoglycan with (L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimelate) tripeptide + H+ + di-trans,octa-cis-undecaprenyl diphosphate |
| No genes |
| a nascent peptidoglycan with L,D cross links (meso-diaminopimelate containing)→a mature peptidoglycan with L,D cross-links (meso-diaminopimelate containing) + H+ + di-trans,octa-cis-undecaprenyl diphosphate |
| No genes |
| a nascent peptidoglycan with (L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimeloyl-glycine) tetrapeptide→a mature peptidoglycan with (L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimeloyl-glycine) tetrapeptide + H+ + di-trans,octa-cis-undecaprenyl diphosphate |
| No genes |
Links:
Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information