MetaCyc Pathway: chorismate biosynthesis from 3-dehydroquinate in Escherichia coli ECOR38

Add experiment(s):


3-dehydroquinate dehydratase:
3-dehydroquinate→3-dehydroshikimate + H2O
(EC 4.2.1.10)
HEPCGN_05580 (aroD)
HEPCGN_19525 (eno)
Shikimate dehydrogenase (in reverse):
3-dehydroshikimate + NADPH + H+→shikimate + NADP+
(EC 1.1.1.25)
HEPCGN_05585 (ydiB)
HEPCGN_11860
HEPCGN_16385 (aroE)
Shikimate kinase:
shikimate + ATP→shikimate 3-phosphate + ADP + H+
(EC 2.7.1.71)
HEPCGN_07240 (aroL)
HEPCGN_15930 (aroK)
3-phosphoshikimate 1-carboxyvinyltransferase:
shikimate 3-phosphate + phosphoenolpyruvate→5-enolpyruvoyl-shikimate 3-phosphate + phosphate
(EC 2.5.1.19)
HEPCGN_23035 (aroA)
Chorismate synthase:
5-enolpyruvoyl-shikimate 3-phosphate→chorismate + phosphate
(EC 4.2.3.5)
HEPCGN_21820 (aroC)

Links:

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information