MetaCyc Pathway: pseudouridine degradation in Escherichia coli ECOR38

Pseudouridine kinase:
pseudouridine + ATP→pseudouridine 5'-phosphate + ADP + H⁺ (EC 2.7.1.83)

Pseudouridylate synthase (in reverse):
pseudouridine 5'-phosphate + H₂O→uracil + D-ribofuranose 5-phosphate (EC 4.2.1.70)

HEPCGN_08795 (rluA)

HEPCGN_11820 (rluF)

HEPCGN_14105 (psuG)

HEPCGN_17000 (truB)

HEPCGN_19465 (truC)

HEPCGN_20375 (rluD)

HEPCGN_21875 (truA)

HEPCGN_22625 (rsuA)

HEPCGN_22720 (psuG)

HEPCGN_23865 (rluC)

HEPCGN_24230 (rluE)

HEPCGN_25560 (rluB)

Links:

Pathway details at MetaCyc
Fitness data for 15 genes
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All MetaCyc pathways for Escherichia coli ECOR38

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information