MetaCyc Pathway: inosine 5'-phosphate degradation in Escherichia coli ECOR38

Add experiment(s):


IMP dehydrogenase:
IMP + NAD+ + H2O→XMP + NADH + H+ (EC 1.1.1.205)
HEPCGN_20900 (guaB)
5'-nucleotidase:
XMP + H2O→xanthosine + phosphate (EC 3.1.3.5)
HEPCGN_06730 (ushA)
HEPCGN_09290 (yjjG)
HEPCGN_11525 (aphA)
HEPCGN_12315
HEPCGN_12325
HEPCGN_12330
HEPCGN_19660 (surE)
HEPCGN_22025 (yfbR)
Purine-nucleoside phosphorylase:
xanthosine + phosphate→xanthine + α-D-ribose-1-phosphate (EC 2.4.2.1)
HEPCGN_07225 (ppnP)
HEPCGN_09220 (deoD)
HEPCGN_21430 (xapA)
Xanthine dehydrogenase:
xanthine + NAD+ + H2O→urate + NADH + H+ (EC 1.17.1.4)
HEPCGN_18990 (xdhC)
HEPCGN_18995 (xdhB)
HEPCGN_19000 (xdhA)

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information