MetaCyc Pathway: methylglyoxal degradation I in Escherichia coli ECOR38

Lactoylglutathione lyase (in reverse):
methylglyoxal + glutathione→(R)-S-lactoylglutathione (EC 4.4.1.5)

HEPCGN_05815

Hydroxyacylglutathione hydrolase:
(R)-S-lactoylglutathione + H₂O→(R)-lactate + glutathione + H⁺ (EC 3.1.2.6)

HEPCGN_07920 (gloB)

HEPCGN_22780 (yeiG)

HEPCGN_23135 (gloC)

(R)-lactate_[in] + an electron-transfer quinone→pyruvate_[in] + an electron-transfer quinol (EC 1.1.5.12)

No genes

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Pathway details at MetaCyc
Fitness data for 4 genes
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All MetaCyc pathways for Escherichia coli ECOR38

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information