MetaCyc Pathway: superpathway of purines degradation in plants in Escherichia coli ECOR38

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Adenosine-phosphate deaminase:
AMP + H+ + H2O→IMP + ammonium (EC 3.5.4.17; 3.5.4.6)
No genes
5'-nucleotidase:
GMP + H2O→guanosine + phosphate (EC 3.1.3.5)
HEPCGN_06730 (ushA)
HEPCGN_09290 (yjjG)
HEPCGN_11525 (aphA)
HEPCGN_12315
HEPCGN_12325
HEPCGN_12330
HEPCGN_15885 (yrfG)
HEPCGN_19660 (surE)
HEPCGN_22025 (yfbR)
Guanosine deaminase:
guanosine + H+ + H2O→xanthosine + ammonium (EC 3.5.4.15)
No genes
IMP dehydrogenase:
IMP + NAD+ + H2O→XMP + NADH + H+ (EC 1.1.1.205)
HEPCGN_20900 (guaB)
5'-nucleotidase:
IMP + H2O→inosine + phosphate (EC 3.1.3.5; 3.1.3.99)
HEPCGN_06730 (ushA)
HEPCGN_07265 (phoA)
HEPCGN_09290 (yjjG)
HEPCGN_11525 (aphA)
HEPCGN_12315
HEPCGN_12325
HEPCGN_12330
HEPCGN_15885 (yrfG)
HEPCGN_19660 (surE)
HEPCGN_22025 (yfbR)
Purine nucleosidase:
guanosine + H2O→guanine + D-ribofuranose (EC 3.2.2.1)
HEPCGN_00955 (rihA)
HEPCGN_08945 (rihC)
HEPCGN_22735 (rihB)
Guanine deaminase:
guanine + H+ + H2O→xanthine + ammonium (EC 3.5.4.3)
HEPCGN_18915 (guaD)
Inosine nucleosidase:
inosine + H2O→hypoxanthine + D-ribofuranose (EC 3.2.2.2)
HEPCGN_00955 (rihA)
HEPCGN_08945 (rihC)
HEPCGN_22735 (rihB)
5'-nucleotidase:
XMP + H2O→xanthosine + phosphate (EC 3.1.3.5)
HEPCGN_06730 (ushA)
HEPCGN_09290 (yjjG)
HEPCGN_11525 (aphA)
HEPCGN_12315
HEPCGN_12325
HEPCGN_12330
HEPCGN_19660 (surE)
HEPCGN_22025 (yfbR)
Xanthine dehydrogenase:
hypoxanthine + NAD+ + H2O→xanthine + NADH + H+ (EC 1.17.1.4)
HEPCGN_18990 (xdhC)
HEPCGN_18995 (xdhB)
HEPCGN_19000 (xdhA)
Purine nucleosidase:
xanthosine + H2O→xanthine + D-ribofuranose (EC 3.2.2.1)
HEPCGN_00955 (rihA)
HEPCGN_08945 (rihC)
HEPCGN_22735 (rihB)
Xanthine dehydrogenase:
xanthine + NAD+ + H2O→urate + NADH + H+ (EC 1.17.1.4)
HEPCGN_18990 (xdhC)
HEPCGN_18995 (xdhB)
HEPCGN_19000 (xdhA)
Urate oxidase:
urate + dioxygen + H2O→(S)-5-hydroxyisourate + hydrogen peroxide (EC 1.7.3.3)
No genes
Hydroxyisourate hydrolase:
(S)-5-hydroxyisourate + H2O→(S)-2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline + H+ (EC 3.5.2.17)
HEPCGN_03920 (hiuH)
(S)-2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline + H+→(S)-(+)-allantoin + CO2 (EC 4.1.1.97)
No genes
Allantoinase:
(S)-(+)-allantoin + H2O→allantoate + H+ (EC 3.5.2.5)
HEPCGN_06540 (allB)
Allantoicase:
allantoate + H2O→(S)-ureidoglycolate + urea (EC 3.5.3.4)
No genes
Ureidoglycolate lyase:
(S)-ureidoglycolate→glyoxylate + urea (EC 4.3.2.3)
HEPCGN_06570 (allA)

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information