MetaCyc Pathway: Bifidobacterium shunt in Escherichia coli ECOR38

Add experiment(s):


Hexokinase:
D-glucopyranose + ATP→D-glucopyranose 6-phosphate + ADP + H+ (EC 2.7.1.1; 2.7.1.2)
HEPCGN_07205 (mak)
HEPCGN_21530 (glk)
Glucose-6-phosphate isomerase:
α-D-glucose 6-phosphate→β-D-fructofuranose 6-phosphate (EC 5.3.1.9)
HEPCGN_11685 (pgi)
HEPCGN_19590 (kduI)
Fructose-6-phosphate phosphoketolase:
β-D-fructofuranose 6-phosphate + phosphate→acetyl phosphate + D-erythrose 4-phosphate + H2O (EC 4.1.2.22)
No genes
Acetate kinase (in reverse):
acetyl phosphate + ADP→acetate + ATP (EC 2.7.2.1; 2.7.2.15)
HEPCGN_04755 (purT)
HEPCGN_17245 (tdcD)
HEPCGN_21185 (eutP)
HEPCGN_21190 (eutQ)
HEPCGN_22000 (ackA)
Transaldolase (in reverse):
D-erythrose 4-phosphate + β-D-fructofuranose 6-phosphate→D-sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate (EC 2.2.1.2)
HEPCGN_01905 (fsa)
HEPCGN_09085
HEPCGN_12285 (fsa)
HEPCGN_21170 (tal)
Transketolase:
D-sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate→D-ribose 5-phosphate + D-xylulose 5-phosphate (EC 2.2.1.1)
HEPCGN_10920
HEPCGN_10925
HEPCGN_18630 (tkt)
HEPCGN_21165 (tkt)
Ribose-5-phosphate isomerase:
D-ribose 5-phosphate→D-ribulose 5-phosphate (EC 5.3.1.6)
HEPCGN_11335 (rpiB)
HEPCGN_18755 (rpiA)
Ribulose-phosphate 3-epimerase:
D-ribulose 5-phosphate→D-xylulose 5-phosphate (EC 5.1.3.1)
HEPCGN_15950 (rpe)
Phosphoketolase:
D-xylulose 5-phosphate + phosphate→acetyl phosphate + D-glyceraldehyde 3-phosphate + H2O (EC 4.1.2.9)
No genes
Glyceraldehyde-3-phosphate dehydrogenase (phosphorylating):
D-glyceraldehyde 3-phosphate + NAD+ + phosphate→3-phospho-D-glyceroyl phosphate + NADH + H+ (EC 1.2.1.12)
HEPCGN_05120 (gapA)
HEPCGN_26125 (gap)
Phosphoglycerate kinase (in reverse):
3-phospho-D-glyceroyl phosphate + ADP→3-phospho-D-glycerate + ATP (EC 2.7.2.3)
HEPCGN_18700 (pgk)
3-phospho-D-glycerate→2-phospho-D-glycerate (EC 5.4.2.12)
HEPCGN_01540 (gpmA)
HEPCGN_09160
HEPCGN_14575 (gpmM)
Phosphopyruvate hydratase:
2-phospho-D-glycerate→phosphoenolpyruvate + H2O (EC 4.2.1.11)
HEPCGN_19525 (eno)
Pyruvate kinase (in reverse):
phosphoenolpyruvate + ADP + H+→pyruvate + ATP (EC 2.7.1.40)
HEPCGN_04725 (pyk)
HEPCGN_05675 (pykF)
L-lactate dehydrogenase (in reverse):
pyruvate + NADH + H+→(S)-lactate + NAD+ (EC 1.1.1.27)
HEPCGN_07625 (ykgF)
HEPCGN_07630 (ykgE)
HEPCGN_10705
HEPCGN_10710

Links:

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information