MetaCyc Pathway: uracil degradation III in Escherichia coli ECOR27

uracil + FMNH2 + NADH + dioxygen→(Z)-3-ureidoacrylate + FMN + NAD+ + H+ + H2O (EC 1.14.99.46)

NOLOHH_21515 (rutA)

(Z)-3-ureidoacrylate + H2O→carbamate + (Z)-3-aminoacrylate + H+ (EC 3.5.1.110)

NOLOHH_21520 (rutB)

carbamate + 2 H+→CO2 + ammonium (spontaneous) (EC 3.5.1.110; 3.5.1.20; 3.5.1.54; 4.2.1.104)

NOLOHH_01730 (cynS)

NOLOHH_23385 (pxpC)

NOLOHH_23390 (pxpB)

(Z)-3-aminoacrylate + H+ + H2O→3-oxopropanoate + ammonium (spontaneous)

NOLOHH_21525 (rutC)

3-oxopropanoate + NADPH + H+→3-hydroxypropanoate + NADP+ (EC 1.1.1.298)

NOLOHH_18640 (ydfG)

NOLOHH_21535 (rutE)

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information