MetaCyc Pathway: peptidoglycan recycling II in Escherichia coli ECOR27

Add experiment(s):


a mature peptidoglycan (meso-DAP containing)→a mature peptidoglycan (meso-DAP containing) + GlcNAc-1,6-anhMurNAc-L-Ala-γ-D-Glu-meso-DAP-D-Ala (EC 4.2.2.f)
NOLOHH_02330 (mltD)
NOLOHH_03500 (sltY)
NOLOHH_11050 (mltC)
NOLOHH_11970 (mltA)
NOLOHH_12535 (mltB)
NOLOHH_13140 (mltF)
NOLOHH_20700 (emtA)
GlcNAc-1,6-anhMurNAc-L-Ala-γ-D-Glu-meso-DAP-D-Ala[out] + H+[out]→GlcNAc-1,6-anhMurNAc-L-Ala-γ-D-Glu-meso-DAP-D-Ala[in] + H+[in]
NOLOHH_01290 (ampG)
N-acetylmuramoyl-L-alanine amidase:
GlcNAc-1,6-anhMurNAc-L-Ala-γ-D-Glu-meso-DAP-D-Ala + H2ON-acetyl-β-D-glucosamine-1,6-anhydro-N-acetyl-β-D-muramate + L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanine
(EC 3.5.1.28)
NOLOHH_02870 (ampD)
NOLOHH_04535 (amiB)
NOLOHH_11950 (amiC)
NOLOHH_13780 (amiA)
NOLOHH_22260 (amiD)
Beta-N-acetylhexosaminidase:
N-acetyl-β-D-glucosamine-1,6-anhydro-N-acetyl-β-D-muramate + H2O→1,6-anhydro-N-acetyl-β-D-muramate + N-acetyl-D-glucosamine
(EC 3.2.1.52)
NOLOHH_21035 (nagZ)
Muramoyltetrapeptide carboxypeptidase:
L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanine + H2O→L-alanyl-γ-D-glutamyl-meso-diaminopimelate + D-alanine
(EC 3.4.17.13)
NOLOHH_20705 (ldcA)
1,6-anhydro-N-acetyl-β-D-muramate + ATP + H2ON-acetyl-D-muramate 6-phosphate + ADP + H+ (EC 2.7.1.170)
NOLOHH_18005 (anmK)
N-acetyl-D-muramate 6-phosphate + H2ON-acetyl-D-muramate + phosphate (EC 3.1.3.105)
No genes
N-acetyl-D-muramate + ATPN-acetyl-α-D-muramate 1-phosphate + ADP + H+ (EC 2.7.1.221)
No genes
N-acetyl-α-D-muramate 1-phosphate + H+ + UDP→UDP-N-acetyl-α-D-muramate + phosphate (EC 2.7.7.99)
No genes
L-alanyl-γ-D-glutamyl-meso-diaminopimelate + UDP-N-acetyl-α-D-muramate + ATP→UDP-MurNAc-L-Ala-γ-D-Glu-meso-DAP + ADP + H+ + phosphate (EC 6.3.2.45)
NOLOHH_04200 (mpl)

Links:

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information