MetaCyc Pathway: superpathway of anaerobic sucrose degradation in Escherichia coli ECOR27

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Sucrose synthase (in reverse):
sucrose + H+ + UDP→β-D-fructofuranose + UDP-α-D-glucose (EC 2.4.1.13)
No genes
Fructokinase:
β-D-fructofuranose + ATP→β-D-fructofuranose 6-phosphate + ADP + H+ (EC 2.7.1.4)
NOLOHH_01495 (mak)
NOLOHH_06155 (yihV)
NOLOHH_14150 (cscK)
UTP-monosaccharide-1-phosphate uridylyltransferase (in reverse):
UDP-α-D-glucose + diphosphate→α-D-glucopyranose 1-phosphate + H+ + UTP (EC 2.7.7.64; 2.7.7.9)
NOLOHH_15735 (galF)
NOLOHH_20460 (galU)
6-phosphofructokinase:
β-D-fructofuranose 6-phosphate + ATP→β-D-fructofuranose 1,6-bisphosphate + ADP + H+ (EC 2.7.1.11)
NOLOHH_05965 (pfkA)
NOLOHH_17555 (pfkB)
Phosphoglucomutase:
α-D-glucopyranose 1-phosphate→D-glucopyranose 6-phosphate (EC 5.4.2.2)
NOLOHH_09870 (glmM)
NOLOHH_23480 (pgm)
Fructose-bisphosphate aldolase:
β-D-fructofuranose 1,6-bisphosphate→glycerone phosphate + D-glyceraldehyde 3-phosphate (EC 4.1.2.13)
NOLOHH_11305 (fbaA)
NOLOHH_15445 (fbaB)
Fructose-bisphosphatase:
β-D-fructofuranose 1,6-bisphosphate + H2O→β-D-fructofuranose 6-phosphate + phosphate (EC 3.1.3.11)
NOLOHH_01550 (phoA)
NOLOHH_04205 (fbp)
NOLOHH_05915 (glpX)
NOLOHH_11255 (glpX)
NOLOHH_23110 (ybhA)
Glucose-6-phosphate isomerase:
α-D-glucose 6-phosphate→β-D-fructofuranose 6-phosphate (EC 5.3.1.9)
NOLOHH_05335 (pgi)
NOLOHH_11805 (kduI)
Triose-phosphate isomerase (in reverse):
glycerone phosphate→D-glyceraldehyde 3-phosphate (EC 5.3.1.1)
NOLOHH_05945 (tpiA)
Glyceraldehyde-3-phosphate dehydrogenase (phosphorylating):
D-glyceraldehyde 3-phosphate + NAD+ + phosphate→3-phospho-D-glyceroyl phosphate + NADH + H+ (EC 1.2.1.12)
NOLOHH_17260 (gapA)
NOLOHH_19375 (gap)
Phosphoglycerate kinase (in reverse):
3-phospho-D-glyceroyl phosphate + ADP→3-phospho-D-glycerate + ATP (EC 2.7.2.3)
NOLOHH_11300 (pgk)
3-phospho-D-glycerate→2-phospho-D-glycerate (EC 5.4.2.12)
NOLOHH_03485
NOLOHH_07615 (gpmM)
NOLOHH_23165 (gpmA)
3-phospho-D-glycerate→2-phospho-D-glycerate (EC 5.4.2.11)
NOLOHH_23165 (gpmA)
Phosphopyruvate hydratase:
2-phospho-D-glycerate→phosphoenolpyruvate + H2O (EC 4.2.1.11)
NOLOHH_12150 (eno)
Pyruvate kinase (in reverse):
phosphoenolpyruvate + ADP + H+→pyruvate + ATP (EC 2.7.1.40)
NOLOHH_16835 (pyk)
NOLOHH_17810 (pykF)
L-lactate dehydrogenase (in reverse):
pyruvate + NADH + H+→(S)-lactate + NAD+ (EC 1.1.1.27)
NOLOHH_01915 (ykgF)
NOLOHH_01920 (ykgE)
Pyruvate, water dikinase:
pyruvate + ATP + H2O→phosphoenolpyruvate + AMP + 2 H+ + phosphate (EC 2.7.9.2)
NOLOHH_17665 (ppsA)
Pyruvate decarboxylase:
pyruvate + H+→acetaldehyde + CO2 (EC 4.1.1.1)
No genes
Alcohol dehydrogenase (in reverse):
acetaldehyde + NADH + H+→ethanol + NAD+ (EC 1.1.1.1)
NOLOHH_01650 (frmA)
NOLOHH_01805 (yahK)
NOLOHH_04010 (ahr)
NOLOHH_07750 (yiaY)
NOLOHH_09500 (acuI)
NOLOHH_19040 (adhP)
NOLOHH_20445 (adhE)

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information